{"_buckets": {"deposit": "90c4fd94-df26-4f91-903f-77b5520abf0c"}, "_deposit": {"created_by": 15, "id": "76", "owners": [15], "pid": {"revision_id": 0, "type": "depid", "value": "76"}, "status": "published"}, "_oai": {"id": "oai:tohoku-mpu.repo.nii.ac.jp:00000076", "sets": ["14"]}, "author_link": [], "control_number": "76", "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2010-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "57", "bibliographicPageEnd": "65", "bibliographicPageStart": "61", "bibliographic_titles": [{"bibliographic_title": "東北薬科大学研究誌", "bibliographic_titleLang": "ja"}, {"bibliographic_title": "Journal of Tohoku Pharmaceutical University", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "佐々木, 健郎", "creatorNameLang": "ja"}, {"creatorName": "ササキ, ケンロウ", "creatorNameLang": "ja-Kana"}, {"creatorName": "SASAKI, KENROH", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "小林, 匡子", "creatorNameLang": "ja"}, {"creatorName": "コバヤシ, キョウコ", "creatorNameLang": "ja-Kana"}, {"creatorName": "KOBAYASHI, KYOKO", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "川島, 美香", "creatorNameLang": "ja"}, {"creatorName": "カワシマ, ミカ", "creatorNameLang": "ja-Kana"}, {"creatorName": "KAWASHIMA, MIKA", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "佐藤, 紘子", "creatorNameLang": "ja"}, {"creatorName": "サトウ, ヒロコ", "creatorNameLang": "ja-Kana"}, {"creatorName": "SATO, HIROKO", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "吉﨑, 文彦", "creatorNameLang": "ja"}, {"creatorName": "ヨシザキ, フミヒコ", "creatorNameLang": "ja-Kana"}, {"creatorName": "YOSHIZAKI, FUMIHIKO", "creatorNameLang": "en"}]}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "The influence of Callistemon rigidus (Myrtaceae) on rat lung activated matrix matalloproteinase-2 (MMP-2) was examined. Methanol extracts from stem and fruit showed inhibitory effects on MMP-2.Activation was induced by p-aminophenylmercuric acetate,and inhibition was measired by using sodium dodecyl sulfate polyacrylamid gel electrophoresis gelatin zymography.The IC50 values were 2.96 and 32.0mg/mL,respectively. Piceatannol was isolated as the active constituent from the stem of this plant,and its IC50 value was 757.1μM. The usefulness of Callistemon rigidus as a supply source of piceatannol is noted,and utility of piceatannol for the investigation of the inhibition of activated MMP-2 was also expected for the prevention and treatment of various diseases concerned with excess activation of MMP.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA1149311X", "subitem_source_identifier_type": "NCID"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2010-12-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00007291389.pdf", "filesize": [{"value": "935.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 935300.0, "url": {"label": "KJ00007291389", "objectType": "fulltext", "url": "https://tohoku-mpu.repo.nii.ac.jp/record/76/files/KJ00007291389.pdf"}, "version_id": "b0189459-9d58-4ac3-8583-84e818a48805"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Callistemon rigidus ; piceatannol ; matrix matalloproteinase-2 ; rat lung ; gelatin zymograpy", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "マキバブラシノキ Callistemon rigidusのマトリックスメタロプロテアーゼ-2阻害作用", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "マキバブラシノキ Callistemon rigidusのマトリックスメタロプロテアーゼ-2阻害作用", "subitem_title_language": "ja"}, {"subitem_title": "Constituent of Callistemon rigidus Showing an Inhibitory Effect on Activated Matrix Metalloproteinase-2", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "15", "path": ["14"], "permalink_uri": "https://tohoku-mpu.repo.nii.ac.jp/records/76", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-12-01"}, "publish_date": "2010-12-01", "publish_status": "0", "recid": "76", "relation": {}, "relation_version_is_last": true, "title": ["マキバブラシノキ Callistemon rigidusのマトリックスメタロプロテアーゼ-2阻害作用"], "weko_shared_id": -1}