@article{oai:tohoku-mpu.repo.nii.ac.jp:00000076,
 author = {佐々木, 健郎 and Sasaki, Kenroh and 小林, 匡子 and Kobayashi, Kyoko and 川島, 美香 and Kawashima, Mika and 佐藤, 紘子 and Sato, Hiroko and 吉﨑, 文彦 and Yoshizaki, Fumihiko},
 issue = {57},
 journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University},
 month = {Dec},
 note = {The influence of Callistemon rigidus (Myrtaceae) on rat lung activated matrix matalloproteinase-2 (MMP-2) was examined. Methanol extracts from stem and fruit showed inhibitory effects on MMP-2.Activation was induced by p-aminophenylmercuric acetate,and inhibition was measired by using sodium dodecyl sulfate polyacrylamid gel electrophoresis gelatin zymography.The IC50 values were 2.96 and 32.0mg/mL,respectively. Piceatannol was isolated as the active constituent from the stem of this plant,and its IC50 value was 757.1μM. The usefulness of Callistemon rigidus as a supply source of piceatannol is noted,and utility of piceatannol for the investigation of the inhibition of activated MMP-2 was also expected for the prevention and treatment of various diseases concerned with excess activation of MMP.},
 pages = {61--65},
 title = {マキバブラシノキ Callistemon rigidusのマトリックスメタロプロテアーゼ-2阻害作用},
 year = {2010},
 yomi = {ササキ, ケンロウ and コバヤシ, キョウコ and カワシマ, ミカ and サトウ, ヒロコ and ヨシザキ, フミヒコ}
}