| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2020-06-15 |
| タイトル |
|
|
タイトル |
【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～ |
|
言語 |
ja |
| タイトル |
|
|
タイトル |
A Case of Decompensated Cirrhosis in which Hepatic Encephalopathy Was Prevented Using Rifaximin and Multiple Laxatives 〜Defecation Control through Continuous Physical Assessment by Pharmacists〜 |
|
言語 |
en |
| 言語 |
|
|
言語 |
jpn |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hepatic encephalopathy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
rifaximin |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
management of defecation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
physical assessment |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
bowel sounds |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| 著者 |
関根, 僚也
高橋, 将典
薄井, 健介
岡田, 浩司
小暮, 高之
佐藤, 賢一
久下, 周佐
渡辺, 善照
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Hepatic encephalopathy is often seen in patients with chronic liver disease. It is prognosis after onset is poor, and it is associated with significant mortality. In addition, it has a strong relationship with constipation, and,defecation management is important. Currently, the European Association for the Study of Liver and American Association for Study of Liver Diseases guidelines for the treatment of chronic liver disease hepatic encephalopathy recommend two to three defecations per day. However, frequent defecation is a burden on patients. in Japan, rifaximin, a non-absorbable antibacterial drug, was recently launched. As a result, the treatment of hepatic encephalopathy, which mainly involves lactulose, has been reviewed. in this case, the effect of combined use of rifaximin and a laxative against hepatic encephalopathy ware examined by evaluating intestinal peristalsis using astethoscope. This treatment prevented hepatic encephalopathy in the current case, despite the patient only defecating once a day. This approach was considered to be effective because the combined use of rifaximin suppressed the increase in the patient s blood ammonia concentration. In addition, the continuous recording of the patient s intestinal peristaltic sound confirmed that the risk of constipation had not increase although there had been no loss of intestinal peristaltic movement. These results suggest that the defecation management based on physical examinations conducted by pharmacist might be useful for assessing the risk of complications and quality of life issues in patient with chronic liver disease. |
|
言語 |
en |
| 書誌情報 |
ja : 東北医科薬科大学研究誌
en : Journal of Tohoku Medical and Pharmaceutical University
号 66,
p. 75-82,
発行日 2019-12
|
| 出版者 |
|
|
出版者 |
東北医科薬科大学 |
|
言語 |
ja |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
2432-5724 |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc-nd/3.0/deed.en |
|
権利情報 |
Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～ (1.6 MB)
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