{"created":"2023-06-20T13:11:34.368557+00:00","id":791,"links":{},"metadata":{"_buckets":{"deposit":"b1022fc1-df3e-477c-8109-2999c148d071"},"_deposit":{"created_by":15,"id":"791","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"791"},"status":"published"},"_oai":{"id":"oai:tohoku-mpu.repo.nii.ac.jp:00000791","sets":["3:71"]},"author_link":[],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"66","bibliographicPageEnd":"82","bibliographicPageStart":"75","bibliographic_titles":[{"bibliographic_title":"東北医科薬科大学研究誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Tohoku Medical and Pharmaceutical University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Hepatic encephalopathy is often seen in patients with chronic liver disease. It is prognosis after onset is poor, and it is associated with significant mortality. In addition, it has a strong relationship with constipation, and,defecation management is important. Currently, the European Association for the Study of Liver and American Association for Study of Liver Diseases guidelines for the treatment of chronic liver disease hepatic encephalopathy recommend two to three defecations per day. However, frequent defecation is a burden on patients. in Japan, rifaximin, a non-absorbable antibacterial drug, was recently launched. As a result, the treatment of hepatic encephalopathy, which mainly involves lactulose, has been reviewed. in this case, the effect of combined use of rifaximin and a laxative against hepatic encephalopathy ware examined by evaluating intestinal peristalsis using astethoscope. This treatment prevented hepatic encephalopathy in the current case, despite the patient only  defecating once a day. This approach was considered to be effective because the combined use of rifaximin suppressed the increase in the patient s blood ammonia concentration. In addition, the continuous recording of the patient s intestinal peristaltic sound confirmed that the risk of constipation had not increase although there had been no loss of intestinal peristaltic movement. These results suggest that the defecation management based on physical examinations conducted by pharmacist might be useful for assessing the risk of complications and quality of life issues in patient with chronic liver disease.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東北医科薬科大学","subitem_publisher_language":"ja"}]},"item_10002_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","subitem_rights_language":"en","subitem_rights_resource":"https://creativecommons.org/licenses/by-nc-nd/3.0/deed.en"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2432-5724","subitem_source_identifier_type":"PISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"関根, 僚也","creatorNameLang":"ja"},{"creatorName":"セキネ, リョウヤ","creatorNameLang":"ja-Kana"},{"creatorName":"Sekine, Ryoya","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"高橋, 将典","creatorNameLang":"ja"},{"creatorName":"タカハシ, マサノリ","creatorNameLang":"ja-Kana"},{"creatorName":"Takahashi, Masanori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"薄井, 健介","creatorNameLang":"ja"},{"creatorName":"ウスイ, ケンスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Usui, Kensuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"岡田, 浩司","creatorNameLang":"ja"},{"creatorName":"オカダ, コウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Okada, Kouji","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"小暮, 高之","creatorNameLang":"ja"},{"creatorName":"コグレ, タカユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Kogure, Takayuki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"佐藤, 賢一","creatorNameLang":"ja"},{"creatorName":"サトウ, ケンイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Satoh, Kennichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"久下, 周佐","creatorNameLang":"ja"},{"creatorName":"クゲ, シュウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Kuge, Shusuke","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"渡辺, 善照","creatorNameLang":"ja"},{"creatorName":"ワタナベ, ヨシテル","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Yoshiteru","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-06-15"}],"displaytype":"detail","filename":"症例1_関根僚也.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～","objectType":"fulltext","url":"https://tohoku-mpu.repo.nii.ac.jp/record/791/files/症例1_関根僚也.pdf"},"version_id":"01cbb85b-3c7e-4aa6-9678-e7bf78cea13b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"hepatic encephalopathy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"rifaximin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"management of defecation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"physical assessment","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bowel sounds","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～","subitem_title_language":"ja"},{"subitem_title":"A Case of Decompensated Cirrhosis in which Hepatic Encephalopathy Was Prevented Using Rifaximin and Multiple Laxatives 〜Defecation Control through Continuous Physical Assessment by Pharmacists〜","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"15","path":["71"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-06-15"},"publish_date":"2020-06-15","publish_status":"0","recid":"791","relation_version_is_last":true,"title":["【症例報告】非代償性肝硬変患者に対してリファキシミンと複数の瀉下薬使用により肝性脳症の回避を試みた一例～薬剤師による継続的なフィジカルアセスメントを通した排便コントロール～"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-03-03T23:40:53.392191+00:00"}