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免疫グロブリン結合糖鎖の構造−機能相関
https://tohoku-mpu.repo.nii.ac.jp/records/784
https://tohoku-mpu.repo.nii.ac.jp/records/78454df4bec-26e5-4758-96b8-69f662b835d1
名前 / ファイル | ライセンス | アクション |
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免疫グロブリン結合糖鎖の構造−機能相関 (3.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||
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公開日 | 2020-06-12 | |||||||||||
タイトル | ||||||||||||
言語 | ja | |||||||||||
タイトル | 免疫グロブリン結合糖鎖の構造−機能相関 | |||||||||||
タイトル | ||||||||||||
言語 | en | |||||||||||
タイトル | Structure-Function Relationship of Immunoglobulin Glycan | |||||||||||
言語 | ||||||||||||
言語 | jpn | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | antibody | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Fc receptor | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | N-glycan | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | immunoglobulin | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | dynamics | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | departmental bulletin paper | |||||||||||
著者 |
山口, 芳樹
× 山口, 芳樹
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Antibodies are glycosylated proteins which play a central role in immune system. much attention has been paid for N-glycosylation at asn297 of igg Fc. it has been well established that the Fc N-glycan is essential for expressingproper effector functions such as Fc receptor binding and complement activation. The underlying mechanism how the N-glycan affect Fc receptor binding has been analyzed and discussed from the structural data. This review will focus on the current understanding how Fc N-glycosylation impacts on the structure and function of the Fc. Finally, techniques are introduced to remodel the N-glycan attached to Fc. | |||||||||||
言語 | en | |||||||||||
書誌情報 |
ja : 東北医科薬科大学研究誌 en : Journal of Tohoku Medical and Pharmaceutical University 号 66, p. 11-18, 発行日 2019-12 |
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出版者 | ||||||||||||
言語 | ja | |||||||||||
出版者 | 東北医科薬科大学 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | PISSN | |||||||||||
収録物識別子 | 2432-5724 | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報Resource | https://creativecommons.org/licenses/by-nc-nd/3.0/deed.en | |||||||||||
権利情報 | Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0) | |||||||||||
著者版フラグ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |