@article{oai:tohoku-mpu.repo.nii.ac.jp:00000870, author = {富田, 和男 and Tomita, Kazuo and 桑原, 義和 and Kuwahara, Yoshikazu and 古川, 紗圭 and Furukawa, Sayaka and 野口, 和行 and Noguchi, Kazuyuki and 栗政, 明弘 and Kurimasa, Akihiro and 佐藤, 友昭 and Sato, Tomoaki}, issue = {69}, journal = {東北医科薬科大学研究誌, Journal of Tohoku Medical and Pharmaceutical University}, month = {Dec}, note = {Ergothioneine(EGT)is a hydrophilic sulfur-containing amino acid and can directly remove reactive oxygen species. More than 100 years have passed since its discovery. Although EGT has a high antioxidant capacity, its role in vivo has not been clarified yet. EGT exists in the bodies of animals and plants, including humans, but animals cannot biosynthesize EGT themselves. Animals have an EGT transporter, which is expressed in organs that are exposed to strong oxidative stress. EGT transporter expresses not only plasma membrane but also mitochondria membrane and protects from oxidative stress. In recent years, it has been reported that EGT is effective against diseases such as neurodegenerative diseases, diabetes, and cancer. EGT is thought to be one of the most important small molecules that may be useful in the diagnosis and treatment of various diseases in the future.}, pages = {11--17}, title = {エルゴチオネインとその生体内作用}, year = {2022}, yomi = {トミタ, カズオ and クワハラ, ヨシカズ and フルカワ, サヤカ and ノグチ, カズユキ and クリマサ, アキヒロ and サトウ, トモアキ} }