@article{oai:tohoku-mpu.repo.nii.ac.jp:00000819, author = {大内, 竜介 and Ouchi, Ryusuke and 今野, 了 and Konno, Ryo and 薄井, 健介 and Usui, Kensuke and 岡田, 浩司 and Okada, Kouji and 綱木, 美由紀 and Tsunaki, Miyuki and 鈴木, 清寿 and Suzuki, Shinju and 長尾, 宗紀 and Nagao, Munenori and 児山, 香 and Koyama, Kaori and 渡辺, 善照 and Watanabe, Yoshiteru}, issue = {67}, journal = {東北医科薬科大学研究誌, Journal of Tohoku Medical and Pharmaceutical University}, month = {Dec}, note = {Methadone is considered to be a highly effective drug for treating cancer pain. However, it has been identified that the complex pharmacokinetics may cause serious side effects such as respiratory depression and QT prolongation associated with overdose. in this study, pharmacists intervened in cases of methadone introduction for intractable cancer pain from the stage of studying the switching method; it was safely conducted from introduction in hospital to continuation in outpatient department. in addition to confirming respiratory status and drowsiness as side effect monitoring, ECG testing by a pharmacist using a simple electrocardiograph was performed;transition to the outpatient department was conducted safely. Pharmacists who understand the pharmaceutical characteristics, mechanism of action, and pharmacokinetics of drugs can contribute to drug therapy and improve patients' quality of life by intervening from a pharmaceutical perspective.}, pages = {73--80}, title = {【症例報告】薬剤師の介入により入院でのメサドン導入から外来での継続までを安全に実施できた1 例}, year = {2020}, yomi = {オオウチ, リュウスケ and コンノ, リョウ and ウスイ, ケンスケ and オカダ, コウジ and ツナキ, ミユキ and スズキ, シンジュ and ナガオ, ムネノリ and コヤマ, カオリ and ワタナベ, ヨシテル} }