@article{oai:tohoku-mpu.repo.nii.ac.jp:00000818, author = {柿沼, 稜 and Kakinuma, Ryo and 藤盛, 寿一 and Fujimori, Juichi and 小林, 理子 and Kobayashi, Michiko and 中村, 正史 and Nakamura, Masashi and 菊池, 大一 and Kikuchi, Hirokazu and 中島, 一郎 and Nakashima, Ichiro}, issue = {67}, journal = {東北医科薬科大学研究誌, Journal of Tohoku Medical and Pharmaceutical University}, month = {Dec}, note = {To clarify the difference of brain atrophy between Parkinson s disease(PD)and progressive supranuclear palsy(PSP), we compared the whole and regional brain volumes between the two disorders comprehensively. We conducted volumetric MRI examinations using Freesurfer software in 36 PD patients and 11 PSP patients to measure the volumes of whole brain and a total of 56 brain regions of interest. As a result, there was no significant difference in age, sex, duration, and severity between the two groups. however, the volumes of cerebral white matter, thalamus, pallidum, diencephalon, cerebellar white mater, and brainstem were significantly decreased and the volume of lateral ventricle, third ventricle, and fourth ventricle were significantly increased in the group of PSP compared to PD(p<0.05). in particular, the volumes of thalamus, diencephalon, cerebellar white matter, brainstem, third ventricle, and fourth ventricle showed the most significant differences between the two groups(p<0.01).}, pages = {69--72}, title = {パーキンソン病と進行性核上性麻痺における脳容積比較}, year = {2020}, yomi = {カキヌマ, リョウ and フジモリ, ジュイチ and コバヤシ, ミチコ and ナカムラ, マサシ and キクチ, ヒロカズ and ナカシマ, イチロウ} }