@article{oai:tohoku-mpu.repo.nii.ac.jp:00000785, author = {桑原, 義和 and Kuwahara, Yoshikazu and 富田, 和男 and Tomita, Kazuo and 高畠, 貴志 and Takabatake, Takashi and 漆原, 佑介 and Urushihara, Yusuke and 五十嵐, 健人 and Igarashi, Kento and 佐藤, 友昭 and Sato, Tomoaki and 栗政, 明弘 and Kurimasa, Akihiro and 福本, 学 and Fukumoto, Manabu}, issue = {66}, journal = {東北医科薬科大学研究誌, Journal of Tohoku Medical and Pharmaceutical University}, month = {Dec}, note = {Radiotherapy is one of the major modalities for the treatment of human cancers and has been established as an excellent local treatment for malignant tumors. To know the molecular mechanisms of radioresistant cells we made a system to compare between radioresistant and sensitive cells with the isogenic background. These cells continue to proliferate under exposure to 2 Gy/day X-rays for more than 30 days. Therefore, we named them clinically relevant radioresistant(CRR)cells. however, molecular mechanisms of CRR cell radioresistance remains to be elucidated so far. in this review new methodologies to know the molecular mechanisms of CRR cell radioresistance will be discussed.}, pages = {19--24}, title = {臨床的放射線耐性細胞のこれまでとこれから}, year = {2019}, yomi = {クワハラ, ヨシカズ and トミタ, カズオ and タカバタケ, タカシ and ウルシハラ, ユウスケ and イガラシ, ケント and サトウ, トモアキ and クリマサ, アキヒロ and フクモト, マナブ} }