{"created":"2023-06-20T13:11:31.522111+00:00","id":734,"links":{},"metadata":{"_buckets":{"deposit":"e1a17d64-bf50-46fa-953f-e38585a987b9"},"_deposit":{"created_by":15,"id":"734","owners":[15],"pid":{"revision_id":0,"type":"depid","value":"734"},"status":"published"},"_oai":{"id":"oai:tohoku-mpu.repo.nii.ac.jp:00000734","sets":["3:69"]},"author_link":[],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-12","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"64","bibliographicPageEnd":"63","bibliographicPageStart":"57","bibliographic_titles":[{"bibliographic_title":"東北医科薬科大学研究誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of Tohoku Medical and Pharmaceutical University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Cristaxenicin A（1）, isolated from the deep sea gorgonian Acanthoprimnoa cristata in 2012 by Nakao et al., is a new xenicane diterpenoid comprised of a 9-membered cyclononene ring and 2-acetoxy-3,4-dihydro-2H-pyran. Toward the total synthesis of 1, we have achieved the synthesis of the αβ, -unsaturated δ-lactone as a model compound bearing a bulky cyclopentanol substituent at α-position. The synthetic approach involves the following key steps: (i) Aldol coupling of cyclopentanone with α-p-methoxybenzyloxy ester, (ii) Swern oxidation of the α-hydroxy ester to afford the α-ketoester, (iii) Julia-Kocienski olefination of the α-ketoester followed by lactonization step.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"東北医科薬科大学","subitem_publisher_language":"ja"}]},"item_10002_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)","subitem_rights_language":"en","subitem_rights_resource":"https://creativecommons.org/licenses/by-nc-nd/3.0/deed.en"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2432-5724","subitem_source_identifier_type":"PISSN"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"中井, 啓陽","creatorNameLang":"ja"},{"creatorName":"ナカイ, ケイヨウ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakai, Keiyo","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Sayar, Noel","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"吉村, 祐一","creatorNameLang":"ja"},{"creatorName":"ヨシムラ, ユウイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Yoshimura, Yuichi","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"渡邉, 一弘","creatorNameLang":"ja"},{"creatorName":"ワタナベ, カズヒロ","creatorNameLang":"ja-Kana"},{"creatorName":"Watanabe, Kazuhiro","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-12-06"}],"displaytype":"detail","filename":"原著1_中井啓陽.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"海洋由来ジテルペン系天然物cristaxenicin A の合成研究：α位に高立体障害の置換基を有するδ-不飽和ラクトン化合物の合成","objectType":"fulltext","url":"https://tohoku-mpu.repo.nii.ac.jp/record/734/files/原著1_中井啓陽.pdf"},"version_id":"a30a6e07-35ba-4b16-8b44-461a9067750f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"cristaxenicin A","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Julia-Kocienski olefination","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"δ-unsaturated lactone","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"海洋由来ジテルペン系天然物cristaxenicin A の合成研究：α位に高立体障害の置換基を有するδ-不飽和ラクトン化合物の合成","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"海洋由来ジテルペン系天然物cristaxenicin A の合成研究：α位に高立体障害の置換基を有するδ-不飽和ラクトン化合物の合成","subitem_title_language":"ja"},{"subitem_title":"Synthetic Study toward Total Synthesis of Marine Diterpenoid Cristaxenicin A: Synthesis of δ-Unsaturated Lactone Bearing α-Bulky Substituent","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"15","path":["69"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-12-06"},"publish_date":"2018-12-06","publish_status":"0","recid":"734","relation_version_is_last":true,"title":["海洋由来ジテルペン系天然物cristaxenicin A の合成研究：α位に高立体障害の置換基を有するδ-不飽和ラクトン化合物の合成"],"weko_creator_id":"15","weko_shared_id":-1},"updated":"2024-03-03T23:41:33.686725+00:00"}