@article{oai:tohoku-mpu.repo.nii.ac.jp:00000044,
 author = {佐々木, 健郎 and Sasaki, Kenroh and 伊東, 宗一 and Ito, So-ichi and 小瀧, 豊司 and Kotaki, Toyoji and 吉崎, 文彦 and Yoshizaki, Fumihiko},
 issue = {50},
 journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University},
 month = {Dec},
 note = {In situ quantitative histochemical analysis on monoamine oxidase (MAO) activity in rat brain and liver was performed for its region specificity. Nitro blue tetrazolium was used for the formazan producing reductive reaction caused by enzymatic degradation product of tryptamine as MAO substrate. A linear relationship was obserbed between the integrated MAO activity and the absorbance analyzed by PC-associated image analysis. The MAO-A inhibitor, clorgylin, inhibited the MAO activity dose-dependently in brain region and liver tissue in vitro and in situ analyses with well correlation. These results suggested that this method could be useful for the quantitative analysis of MAO activity in tissue sections, especially in the rat locus coeruleus that plays an important role in noradrenergic neurons.},
 pages = {125--130},
 title = {In situ酵素組織化学法によるラット脳及び肝Monoamine Oxidase活性の検討},
 year = {2003},
 yomi = {ササキ, ケンロウ and イトウ, ソウイチ and コタキ, トヨジ and ヨシザキ, フミヒコ}
}