@article{oai:tohoku-mpu.repo.nii.ac.jp:00000247, author = {熊谷, 健 and Kumagai, Takeshi and 白澤, 衣理 and Shirosawa, Eri and 堤, 啓 and Tsutsumi, Hiromu and 蝦名, 敬一 and Ebina, Keiichi and 横田, 勝司 and Yokota, Katsushi}, issue = {51}, journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University}, month = {Dec}, note = {We investegated the effects of nine possible endocrine disrupting chemicals (EDCs) on the nitric oxide (NO) production and growth of mouse peritoneal macrophages. Genistein and coumestrol inhibited lipopolysaccharide-induced NO production in macrophages, whereas other EDCs had no effect. In WST-8 assay, the growth of mouse macrophages was induced by 17β-estradiol, bisphenol A, nonylphenol, diethyl phthalete, genistein and daidzein. In addition, the cell viability of daidzein-treated macrophages was 1.7-fold increased as compared with non-treated macrophages. These results suggest that EDCs affect cellular function in macrophages.}, pages = {67--72}, title = {数種の内分泌攪乱化学物質のマウス腹腔マクロファージ細胞機能に及ぼす影響}, year = {2004}, yomi = {クマガイ, タケシ and シロサワ, エリ and ツツミ, ヒロム and エビナ, ケイイチ and ヨコタ, カツシ} }