@article{oai:tohoku-mpu.repo.nii.ac.jp:00000222,
 author = {溝口, 広一 and Mizoguchi, Hirokazu and 成田, 年 and Narita, Minoru and 澤井, 敏樹 and Sawai, Toshiki and 渡辺, 千寿子 and Watanabe, Chizuko and 長瀬, 博 and Nagase, Hiroshi and 櫻田, 忍 and Sakurada, Shinobu},
 issue = {52},
 journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University},
 month = {Dec},
 note = {The involvement of endogenous opioid peptides and opioid receptors in supraspinal site on the antinociception induced by cold water swimming was determined using the mouse tail-flick test. The mice forced to swim in cold water for 3 min, showed the marked antinociception. The antinociception induced by cold water swimming was significantly attenuated by intracerebroventricularly (i.c.v.) pretreatment with antiserum against β-endorphin, but not against dynorphin A or [Leu^5] enkephalin. On the other hand, the antinociception was not affected by i.c.v. pretreatment with μ-opioid receptor antagonists β-funaltrexamine and D-Phe-cyclo-(Cys-Tyr-D-Trp-Orn-Thr-Pen)-Thr-NH_2, δ-opioid receptor antagonists naltrindole, 7-benzylidene naltrexone and naltriben, or κ-opioid receptor antagonist nor-binaltorphimine. The present results suggest that the antinociception induced by cold water swimming may be mainly mediated through the release of β-endorphin in the supraspinal site, which act on β-endorphin-sensitive non-μ-, non-δ-, and non-κ-opioid receptor, so called putative ε-opioid receptor.},
 pages = {105--110},
 title = {冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与},
 year = {2005},
 yomi = {ミゾグチ, ヒロカズ and ナリタ, ミノル and サワイ, トシキ and ワタナベ, チズコ and ナガセ, ヒロシ and サクラダ, シノブ}
}