@article{oai:tohoku-mpu.repo.nii.ac.jp:00000217,
 author = {伴場, 光一 and Banba, Koh-ichi and 中澤, 孝浩 and Nakazawa, Takahiro and 館岡, 礼奈 and Tateoka, Ayana and 大澤, 啓助 and Ohsawa, Keisuke},
 issue = {52},
 journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University},
 month = {Dec},
 note = {As a part of our studies on the metabolic fate of hirsuteine (HT) and hirsutine (HS), the indole alkaloids of Uncaria rhynchophylla, fecal and urinary metabolites of HT and HS were analyzed by a HPLC equipped with a photodiode array detector. Feces samples from rats orally administered HT was found to contain a metabolite. Similarly, feces samples from HS were a metabolite. The metabolites of HT and HS in feces were identified as 11-hydroxyhirusuteine and 11-hydroxyhirusutine by direct comparison with authentic samples on HPLC, respectively. The parent compound was detected from only feces samples from HT. Total cumulative fecal excretion during 72h after the oral administration of HT and HS was approximately 7% and 8%, respectively. On the other hand, urinary excretion during 24h after the intravenous administration of HT and HS was approximately 5% and 12%.},
 pages = {65--72},
 title = {釣藤鉤の主要なインドールアルカロイドhirsuteine及びhirsutineの糞及び尿中代謝物について},
 year = {2005},
 yomi = {バンバ, コウイチ and ナカザワ, タカヒロ and タテオカ, アヤナ and オオサワ, ケイスケ}
}