@article{oai:tohoku-mpu.repo.nii.ac.jp:00000147,
 author = {安保, 明博 and Ambo, Akihiro and 山田, 寿乃 and Yamada, Hisano and 橘, 伸至 and Tachibana, Shinji and 鈴木, 崇司 and Suzuki, Takashi and 久保田, 佳代 and Kubota, Kayo and 佐々木, 有亮 and Sasaki, Yusuke},
 issue = {54},
 journal = {東北薬科大学研究誌, Journal of Tohoku Pharmaceutical University},
 month = {Dec},
 note = {It has recently been shown that oligoarginine or arginine-rich peptides can penetrate into the cells. In this study, we investigated a facile method for preparing an arginine-rich pep tide from salmon protamine sulfate. A 14-amino acid peptide (VSRRRRRRGGRRRR) was obtained by thermolysin digestion in alkaline pyroborate buffer at pH 8.74 and pH 8.93 in a satisfactory yield while the peptide did not obtained in a neutral Tris-HCl buffer at pH 7.40. The 14-amino acid peptide was converted to its N-terminal mercaptopropionyl derivative. The modification serves as a tether by forming disulfide bond with Cys residue for delivery of high molecular weight proteins into the cells.},
 pages = {83--91},
 title = {サケプロタミンからの塩基性ペプチドVSRRRRRRGGRRRRの簡便な調製},
 year = {2007},
 yomi = {アンボ, アキヒロ and ヤマダ, ヒサノ and タチバナ, シンジ and スズキ, タカシ and クボタ, カヨ and ササキ, ユウスケ}
}