{"_buckets": {"deposit": "a9e54058-5127-4f4f-a529-cd46ee14aace"}, "_deposit": {"created_by": 15, "id": "147", "owners": [15], "pid": {"revision_id": 0, "type": "depid", "value": "147"}, "status": "published"}, "_oai": {"id": "oai:tohoku-mpu.repo.nii.ac.jp:00000147", "sets": ["11"]}, "author_link": [], "item_1_biblio_info_14": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2007-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "54", "bibliographicPageEnd": "91", "bibliographicPageStart": "83", "bibliographic_titles": [{"bibliographic_title": "東北薬科大学研究誌", "bibliographic_titleLang": "ja"}, {"bibliographic_title": "Journal of Tohoku Pharmaceutical University", "bibliographic_titleLang": "en"}]}]}, "item_1_creator_6": {"attribute_name": "著者名(日)", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "安保, 明博", "creatorNameLang": "ja"}, {"creatorName": "アンボ, アキヒロ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Ambo, Akihiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "山田, 寿乃", "creatorNameLang": "ja"}, {"creatorName": "ヤマダ, ヒサノ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Yamada, Hisano", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "橘, 伸至", "creatorNameLang": "ja"}, {"creatorName": "タチバナ, シンジ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Tachibana, Shinji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "鈴木, 崇司", "creatorNameLang": "ja"}, {"creatorName": "スズキ, タカシ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Suzuki, Takashi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "久保田, 佳代", "creatorNameLang": "ja"}, {"creatorName": "クボタ, カヨ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Kubota, Kayo", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "佐々木, 有亮", "creatorNameLang": "ja"}, {"creatorName": "ササキ, ユウスケ", "creatorNameLang": "ja-Kana"}, {"creatorName": "Sasaki, Yusuke", "creatorNameLang": "en"}]}]}, "item_1_description_11": {"attribute_name": "抄録(日)", "attribute_value_mlt": [{"subitem_description": "It has recently been shown that oligoarginine or arginine-rich peptides can penetrate into the cells. In this study, we investigated a facile method for preparing an arginine-rich pep tide from salmon protamine sulfate. A 14-amino acid peptide (VSRRRRRRGGRRRR) was obtained by thermolysin digestion in alkaline pyroborate buffer at pH 8.74 and pH 8.93 in a satisfactory yield while the peptide did not obtained in a neutral Tris-HCl buffer at pH 7.40. The 14-amino acid peptide was converted to its N-terminal mercaptopropionyl derivative. The modification serves as a tether by forming disulfide bond with Cys residue for delivery of high molecular weight proteins into the cells.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_1_source_id_13": {"attribute_name": "雑誌書誌ID", "attribute_value_mlt": [{"subitem_source_identifier": "AA1149311X", "subitem_source_identifier_type": "NCID"}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2007-12-01"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "KJ00005384873.pdf", "filesize": [{"value": "738.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_11", "mimetype": "application/pdf", "size": 738700.0, "url": {"label": "KJ00005384873", "objectType": "fulltext", "url": "https://tohoku-mpu.repo.nii.ac.jp/record/147/files/KJ00005384873.pdf"}, "version_id": "e00b893e-1a18-462a-9e13-c11574905f58"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "arginine-rich peptide", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "cell penetrating peptide", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "protamine", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "jpn"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "サケプロタミンからの塩基性ペプチドVSRRRRRRGGRRRRの簡便な調製", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "サケプロタミンからの塩基性ペプチドVSRRRRRRGGRRRRの簡便な調製", "subitem_title_language": "ja"}, {"subitem_title": "A Facile Method for Preparing an Arginine-rich Peptide from Salmon Protamine", "subitem_title_language": "en"}]}, "item_type_id": "1", "owner": "15", "path": ["11"], "permalink_uri": "https://tohoku-mpu.repo.nii.ac.jp/records/147", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2007-12-01"}, "publish_date": "2007-12-01", "publish_status": "0", "recid": "147", "relation": {}, "relation_version_is_last": true, "title": ["サケプロタミンからの塩基性ペプチドVSRRRRRRGGRRRRの簡便な調製"], "weko_shared_id": -1}
サケプロタミンからの塩基性ペプチドVSRRRRRRGGRRRRの簡便な調製
https://tohoku-mpu.repo.nii.ac.jp/records/147
https://tohoku-mpu.repo.nii.ac.jp/records/147